How are NET cancers formed?

How NETs are formed is still not fully understood. As with all forms of cancer, NETs arise when cells multiply rapidly in the body. Normal cells in our body divide in a controlled manner, but in cancer the control signals go wrong. This causes the formation of abnormal cells, which divide quickly resulting in tumor growth.

Most NETs occur without any hereditary link, but there are cases where NETs are present as part of a familial endocrine cancer syndrome such as MEN1, MEN 2, neurofibromatosis type 1 or Von Hippel Lindau.